FOUNDER'S NOTE PORTFOLIO NEX FRONTIERS JOBS

Investment Intelligence

Capital at the
edge of what's next.

A privately held investment firm deploying AI-driven intelligence to identify and back the companies defining the next decade.

Palo Alto Singapore Shanghai

At nex capital, we believe the next decade will be defined by the confluence of artificial intelligence and fundamental human needs. We are not investing in technology for its own sake — we are investing in paradigm shifts. Our thesis is built on the principle of computational leverage: identifying the precise points where algorithmic advances unlock disproportionate value, from personalized medicine to decentralized infrastructure.

We seek out companies that are not merely building good products, but crafting the foundational architectures of the future. This demands a different kind of capital — patient, intelligent, and deeply aligned with the founders who are doing the hardest work. Our commitment is to be the most insightful partner behind the most audacious ideas, ensuring the future arrives faster, and more equitably, than it otherwise would.

This conviction is validated by the performance of our proprietary AI models, which have consistently generated alpha at a scale that surpasses benchmarks set by many of the most distinguished human investors. Our returns are not a market anomaly. They are the direct result of a superior predictive architecture — one that redefines the frontier of what investment intelligence can be.

— The Founder, nex capital

The next decade belongs
to three convergences.

NEX Frontiers is our view into the technological and biological paradigm shifts we believe will create entirely new markets. We are not investing in incremental improvements — we are underwriting foundational science.

I.  Generative Biology

The protein is the new software.

For fifty years, drug discovery operated on a craft model: chemists intuiting molecular structures, biologists running decade-long trials, attrition rates above 90%. The AlphaFold breakthrough — and the wave of generative protein models it catalyzed — changed the fundamental economics of biological design. We can now explore protein space computationally, at a scale and speed that makes the old paradigm look like hand-typesetting.

We are investing at the intersection of large-scale biological foundation models and wet-lab automation — companies that have reduced the design-synthesize-test cycle from months to days. The implications extend far beyond therapeutics: novel enzymes for industrial chemistry, biodegradable materials engineered to specification, agricultural proteins that reshape food production. Generative biology is not a vertical within biotech. It is a new design medium, as general-purpose as software itself.

Our conviction: the firms that control proprietary biological datasets and the models trained on them will occupy a position in the life sciences analogous to what NVIDIA occupies in compute. We are identifying those firms before the market has fully recognized what they are building.

II.  Computational Physics

Simulation is becoming the new experiment.

Physics-informed neural networks, differentiable simulators, and AI-accelerated molecular dynamics are collapsing the boundary between digital model and physical truth. For the first time, it is becoming possible to design a material, a reactor, or an aerodynamic surface entirely in silico — with simulation fidelity high enough that physical prototyping becomes validation rather than exploration.

The implications are enormous. In energy: AI-accelerated plasma simulation is compressing the development timeline for commercial fusion by years. In materials: neural interatomic potentials are enabling the discovery of battery chemistries and structural alloys that deterministic methods would take decades to find. In aerospace: high-fidelity CFD models trained on proprietary flight data are giving defense primes and launch companies design advantages invisible to competitors still running legacy solvers.

We are positioning capital at the companies building the computational infrastructure for this shift — not merely applications, but the simulation engines, training pipelines, and physics-aware foundation models that will become the standard tools of the physical sciences over the next decade.

III.  Decentralized Infrastructure

The architecture of trust is being rewritten.

The original internet was designed for information exchange, not value exchange. Layering financial infrastructure on top of a protocol never designed for it has produced a global financial system that is simultaneously too slow, too expensive, and too geographically contingent. The public blockchain networks that have matured over the past decade are not a speculative asset class — they are an infrastructure replacement cycle.

We invest in the protocols and applications making decentralized infrastructure genuinely useful: high-throughput settlement layers capable of supporting real-world financial volumes, tokenization platforms bringing illiquid assets — real estate, private credit, infrastructure — onto programmable rails, and decentralized physical infrastructure networks (DePIN) proving that blockchain-coordinated hardware can outcompete centralized alternatives on cost and resilience.

The endgame is not crypto as a parallel financial system. It is programmable, composable financial infrastructure that the legacy system will adopt because the economics leave it no choice. We are investing now, while that recognition is still forming.

Palo Alto, CA  ·  Full-Time

Quant AI Analyst

THE ROLE

You will be at the nexus of financial theory, machine learning, and software engineering — developing, testing, and deploying the proprietary algorithms that form the core of our investment engine. This is not a passive role. You will be an active architect of the systems that generate alpha.

RESPONSIBILITIES

  • Research and implement novel ML models (LLMs, reinforcement learning, deep neural networks) for signal generation and portfolio optimization.
  • Mine unconventional datasets to uncover predictive patterns and build durable data moats.
  • Build and maintain high-performance infrastructure for backtesting and live trading.
  • Translate abstract investment theses into automated, quantifiable strategies.

QUALIFICATIONS

  • Advanced degree (Ph.D. or M.S.) in Computer Science, Statistics, Physics, or Mathematics.
  • Demonstrated expertise in ML and statistical modeling; proficiency in Python and relevant libraries.
  • Strong software engineering fundamentals. A first-principles approach to problem-solving.
  • Deep curiosity for finding signals in noise. Prior finance experience a plus, not a requirement.
Apply

Palo Alto, CA  ·  Full-Time

Chief Legal

THE ROLE

You will be the primary legal and strategic advisor, navigating the complex intersection of venture capital, artificial intelligence, and global regulation. You will build the legal architecture that underpins our investment strategy and protects the firm as we operate at the frontier of technology.

RESPONSIBILITIES

  • Lead all legal aspects of investment transactions — deal structuring, due diligence, negotiation, and closing.
  • Advise on fund formation, governance, and regulatory matters (SEC, FinCEN).
  • Develop IP and data rights strategies for AI-driven portfolio companies.
  • Provide strategic counsel to the executive team on corporate risk and emerging AI legal precedents.

QUALIFICATIONS

  • J.D. from a top-tier law school; member of a state bar (California preferred).
  • 10+ years at a leading law firm or in-house at a venture capital, private equity, or technology firm.
  • Deep expertise in M&A, venture financing, and fund structuring.
  • Genuine understanding of the legal and ethical implications of emerging technologies.
Apply